The radiological zoning of Chornobyl contaminated areas was one of Chews the essential elements of social and radiation protection.The zoning was based on estimates of annual committed effective doses to members of the public and on the levels of radionuclide deposition density.In 1991, 86 settlements were classified as associated with the zone of
Fall injuries, associated deaths, and 30-day readmission for subsequent falls are increasing in the elderly US population: a query of the WHO mortality database and National Readmission Database from 2010 to 2014
Colette Galet,1 Yunshu Zhou,2 Patrick Ten Eyck,2 Kathleen S Romanowski1 1Acute Care Surgery Division, Department of Surgery, Iowa City, IA, USA; 2Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA, USA Purpose: Clinicians anecdotally noted that elderly patients who suffered from traumatic injuries (falls or other in
Defining and targeting patterns of T cell dysfunction in inborn errors of immunity
Inborn errors of immunity Beet Root (IEIs) are a group of more than 450 monogenic disorders that impair immune development and function.A subset of IEIs blend increased susceptibility to infection, autoimmunity, and malignancy and are known collectively as primary immune regulatory disorders (PIRDs).While many aspects of immune function are altered
Exosomal EGFR and miR-381-3P Mediate HPV-16 E7 Oncoprotein-Induced Angiogenesis of Non-Small Cell Lung Cancer
Background: It has been demonstrated that exosomes derived from gong HPV-16 E7-over-expressiong non-small cell lung cancer (NSCLC) cells (E7 Exo) trigger increased levels of epidermal growth factor receptor (EGFR) and miR-381-3p.The purpose of this investigation was to examine the role of E7 Exo in NSCLC angiogenesis, and to analyze the contributio
Chemo-tolerance and sensitization by short-term fasting: The autophagy connection
Preclinical studies suggest that fasting prior to chemotherapy may be an effective strategy to protect patients against the adverse effects of chemo-toxicity.Fasting may also sensitize cancer cells to chemotherapy.It is further suggested that fasting may similarly augment the efficacy of oncolytic viral therapy.The primary mechanism mediating these